[decadentcactus]

I've been using wxPython for a desktop client (tied to a website). Initially I tried to make it all by myself, then got a visual creator, and productivity went WAY up.

I used wxFormBuilder: http://sourceforge.net/projects/wxformbuilder/

It's pretty much a point-and-click sort of thing, but after the initial drafting/mockups I tweaked it by hand (small things like names/strings, as well as adding the events). I used Python 2.7 - not sure about 3.2.

If you need any help send me an email and I'll do my best to help. I've managed to compile/run it on Windows ok, and as far as I'm aware it's possible to compile it for Mac/Linux. I just have no Mac to test.

[arocks]

After comparing a lot of cross-platform GUI toolkits in Python, I too settled on wxPython because it gives the closest possible 'native' experience on each platform. It also worked well with Py2EXE and other packaging tools. Would highly recommend that you give it a try.