[Johanx64]

The whole conversation is a version of "does alcohol help with depression better than a placebo?"

Because just like alcohol - so do SSRIs have a very clear, pronounced psychoactive pharmaceutical effects. It's just that both effects have little to do with "depression". For example, setraline is one of the most effective drugs for PE(Premature Ejaculation), with easily measurable effect (it can be timed!).

Do depressed people feel better when they are drunk and inebriated? Maybe, probably some do? There certainly are quite a lot of people that self medicate depression with alcohol!

Do depressed people feel better when they are zombified out of their brain with SSRIs? Probably some do?

From a certain point of view, prescribing SSRIs for depression isn't all that different from prescribing alcohol for depression. Both are hepatotoxic - pretty bad for your liver.

And is just a symptom of stone-age we live in when it comes to medicine and understanding of the human body.