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by ac0111 483 days ago
Thank you so much for this! Would brain biopsies (if they could be performed safely, widely) be more beneficial than the multimodal/multi-omic datasets now emerging that combine PET/CSF/Blood? Also, how much information would PET-ligands designed to bind to fibres and the p-tau blood test yield towards designing interventions? What exactly would they reveal that we don't know already?