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by trashface 489 days ago
Probably not going to be super popular but maybe heating your brain for 20 years? https://text.npr.org/nx-s1-5293253
2 comments

Elevated heat shock proteins actually makes good sense as a reason. We should check ClinicalTrials.gov using the key words: Alzheimer and “heat shock protein”.

I just tried anf found a total of 130 trials using Heat shock proteins 70 or 90 (HSP70 and HSP90) and with very few exceptions they are all cancer trials.

Monoculture.

Sauna sounds good at this point.

Would working out hard (HIIT), that makes the heart rate go up a lot (~180bpm) generate enough heat in the body for a similar effect?

Basically, can I replace sauna with 30 minutes of vigorous cardio?

Edit: I see this was asked already - https://news.ycombinator.com/item?id=43062169

So sauna/Turkish bath/hot-springs users have reduced incidence of Alzheimer's?

If going to the sauna daily is all it takes to prevent it, that would be quite a thing!
Is Alzheimer's less prevalent in sauna going populatioo?
I don't know, but the parent's link article says:

>"I spent 20 years in the Navy, most of it in the hot spots, like the engine rooms of ships—110 degrees is nothing on a ship," he says. That environment may have caused an increase in heat shock proteins, which were able to limit the spread of tau and prevent the onset of Alzheimer's. The scientists studying Whitney aren't sure if that's all, or even part, of the explanation. But they are hoping that the paper on Whitney will encourage other researchers to look for answers.

So instead of going to work for the navy, one could just go to the sauna daily.

Edit: turns out that it might be true: https://academic.oup.com/ageing/article/46/2/245/2654230?log...

According to this it would be the opposite: https://pubmed.ncbi.nlm.nih.gov/28687259/

So maybe Sauna is good, but where Sauna is popular is usually a place that is very cold and humid, which is not good.

Finland has huge toxic algae bloom problems.

The link between BMAA (from toxic algae blooms) and neurodegenerative diseases in predisposed people is basically causal and proven at this point, but it's allegedly suppressed by Big Fishing and Aquaculture.

You may be right. There are many other components contributing to the problem in Finland, too.

I'm in Estonia, should I also be worried about the toxic algae? I had no idea about this.