[JumpCrisscross]

Thank you. That said, CFR’s denominator is those who show up to a hospital in bad enough shape to be tested for H5N1. All we can conclude is this appears more deadly than the flu. That’s concerning, but not what I’d consider “very deadly.”

[PierceJoy]

I think the available evidence supports calling it very deadly to humans. As you said though, it's possible and even likely the CFR is overestimating. However I doubt you would see a 50% CFR equate to something low enough that wouldn't effectively be a disaster if human to human transmission began, and at a rate similar to the flu or covid. Let's pray that never happens or that we have an effective vaccine by that time.

[hedora]

Technically speaking, it cannot be more deadly than the flu, since it is the flu.

There’s some evidence of rapidly expanding asymptomatic human -> human spread of it.

Hopefully that strain acts as an effective vaccine against the one(s) responsible for the > 50% CFR.

[JumpCrisscross]

> it cannot be more deadly than the flu, since it is the flu

I’d say technically it’s not the flu. The flu is influenza A or B.

[Izkata]

There was a post just a day or two ago about the surprising finding of people with antibodies who never got sick. Hopefully they'll chase that down and we'll get a more correct denominator soon.