[mlyle]

Wouldn't be the first time that a syndrome ends up having basically two opposite etiologies.

Abnormal synaptic density-- high or low) producing autism-like social deficits wouldn't be too much of a surprise.

Alternatively, starting with high connectivity resulting in a greater rate of synaptic pruning and overcorrection wouldn't be a surprise, either.

All are interesting things to think about and watch evolve.