We'll see. The Executive Order allows for exemptions, "provided that the department and agency heads shall make exemptions they deem necessary." The big question is what criteria shall be used for those exemptions.
As someone who cares about government efficiency, I hope it’ll service as an escape hatch to help agencies avoid the worst impacts of this policy. But I’m sure it’ll be a a way to reward political appointees with perks that career civil servants don’t get.