[webdigi]

Socket.io works well, we put together this demo where an iPhone is used as a controller for a browser game http://www.webdigi.co.uk/fun/space

[prezjordan]

Dead-simple, too. I only have moderate experience with web applications and I found socket.io extremely approachable.

[SvenBergstrom]

Agreed, i really was blown away the first time I wrote something simple and it just worked... On my phones, my pc and my friends browsers.