Yes, and it's infuriating if software draws the conclusion that, simply because I happen to be in region x (or even worse, using language x), I must also want date presentation, units of temperature and distance etc. to be according to customs in x.
At least macOS/iOS at this point mostly allow customizing many of these, but some native apps and date picker widgets still don't respect my preferences, driving me nuts every time I have to schedule a reminder or meeting.