[dragonwriter]

> With GLP-1 doesn’t this change the calculus?

GLP-1 agonists are not exercise and thus using them would not change the calculus on how common it is to lose “significant weight and actually [keep] it off permanently through exercise.”

Nor does their availability change the validity of GP’s advice.

[ijidak]

Sorry, I was referring to this part:

> Once you reach a new weight, that’s just your body’s new normal.