[kylehotchkiss]

Sure, it'd also be nice to have a small portioned meal that tastes good and meets your needs and satisfies your hunger for longer. Can GLP-1 agonists (intestinal enzyme, so maybe just package it well?) just be added to foods like MSG to achieve this? Like a lactaid but it's a GLP-1 agonists

[xarope]

There are also plenty of ways to have a large portioned meal that tastes good and meets your needs and satisfies your hunger for longer, without having to resort to drugs to curb your appetite.

Greg Doucette's cookbook shows how you can add "bulky" food that are lower in calories. I'm not a fan of the propensity of artificial sweeteners, but the principles are the important thing.

As an aside, I also wonder if this fascination with having "quick fixes" (aka let's add GLP-1 agonists to reduce appetite) is a generational thing, or just that in HN we have a bio-hacking mindset?

It's quite a contrast to the other article in HN today, "An Unreasonable Amount of Time", https://news.ycombinator.com/item?id=42557098

[edit] typos

[kylehotchkiss]

> I also wonder if this fascination with having "quick fixes"

American culture. We want maximum results with minimum effort.

[Scoundreller]

Sure, there’s already oral versions that exist: https://pmc.ncbi.nlm.nih.gov/articles/PMC6969659/

Unsure if it has to be in some stomach-acid resistant packaging or slow release or something though.

[timtas]

You can eat as much meat and tropical fats as it takes to satisfy, and you WILL lose weight and regain metabolic health. The catch is, you gotta ditch most of the carbs.