[jerf]

I've been using Dvorak for about three years (+ Caps Lock -> Backspace for about six months).

I find complaints about keystrokes in emacs to be overrated. I think the problem people have is that even though the keystroke for, say, "go to beginning of the line" may be "CTRL-a", in your brain it manifests as a separate keystroke and will require distinct time to re-learn, even after you've mastered a. Not a lot of time, but time.

I play Angband sometimes (in the laptop keyboard configuration), and for that I always go back to QWERTY, because I don't "press the letter p to pray", I "press the Pray key", and having that remapped and trying to relearn everything is just silly.

Personally, I'm not sure I recommend switching. But if you do switch, I do recommend keeping it. The anecdotal wrist pain mitigation evidence is anecdotal, but since nobody's done a study, it's all we have to go on.