[Zefiroj]

nix-ld[1] and envfs[2] provide a decent workaround for unpatched binaries, in case you haven't heard of these tools yet.

[1] https://github.com/nix-community/nix-ld [2] https://github.com/Mic92/envfs

The blog post linked by [1] is quite good.

[ChocolateGod]

I use NixOS for the base system and Flatpak+Containers for everything else. I would rather keep it this way as it keeps everything nice and separated, and less chance of things breaking from Nix being rolling.