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by infinite8s 547 days ago
What's the current state of the art in terms of being able to regrow teeth/regenerate alveolar bone?
2 comments

One thing is using rapamycin for bone and soft tissue regrowth. The FDA recently approved a human study after previous research showed success in mice.

https://dental.washington.edu/uw-periodontal-study-receives-...

For teeth? The https://pmc.ncbi.nlm.nih.gov/articles/PMC7880588/ Anti-USAG-1 serum.

It's laboratory antibody serum from a specific human-sourced monoclonal cell line. Seems to work on all mammals (notably both nice and ferrets; I'm told their teeth system is widely different evolutionary and that humans are kinda in the middle).

A human study should be ongoing on some children in Japan that for genetic reasons are missing a few adult teeth (never grew).