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by rstuart4133 557 days ago
Sounds like the warnings about GMO.

In the mean time, they tried using mRNA vaccines that did mimic our own mRNA, but they caused immune reaction. Substituting a different nucleoside and made the vaccine more stable. The way pseudouridine is used in mRNA vaccines isn't found in nature, ergo people who have been vaccinated are already carrying around bit bit of a form of life never seen before on the planet.
1 comments
gus_massa 557 days ago
tRNA has a lot of weird nucleotices. I expect no problem with another one, but I'm not a biologist.

From: https://en.wikipedia.org/wiki/Transfer_RNA

> A large number of the individual nucleotides in a tRNA molecule may be chemically modified, often by methylation or deamidation. These unusual bases sometimes affect the tRNA's interaction with ribosomes and sometimes occur in the anticodon to alter base-pairing properties.

link