[tbalsam]

I have chronic fatigue issues and after trying thousands of dollars' worth of supplements over the years what worked best for me were blood glutamate scavengers (N-acetyl cysteine for me, I take an unnaturally high dose of up to 8g a day), which seem to help other chronic fatigue people, as well as berberine & niacinamide.

Other things help me that are specific to me but those definitely had a rather dramatic impact on me (after an initial period of feeling like I'd been hit by a train -- it tended make me experience my fatigue up front instead of as PEMS and also reduce the symptoms of it somewhat)

Taurine is great too, there's also TUDCA which is somewhat legendary in some parts of the fatigue community, very good supplement.

Hope this helps! <3 Doing the personal work of letting go of emotional stressors and ceasing all stimulant use when possible (I know it sounds horrible) was also really hard and made a big impact over the years for me.

Still not perfect but so much more functional than I used to be. <3