Dvorak keyboard's fatal flaw is when you have to type on someone else's keyboard. Standardization has its benefits, even if less than ideal. Trackballs have a similar issue.
I've exclusively used Kensington trackballs at home and work (along with trackpads on laptops I guess) since I was around seven years old, Dvorak since I was around fourteen.
I really don't use other people's computers that often, but mice aren't that hard to use (just uncomfortable) and I can still type in QWERTY at about 25WPM but I'd have to look at the keyboard a bit.
Trackballs and Dvorak are both more comfortable than their alternatives, but the real benefit is the reactions I get when other people try to use MY devices when they're not prepared lol
What about keyboard shortcuts? I’ve only realised why some shortcuts were chosen after using an English language QWERTY keyboard.
On a German QWERTZ keyboard, most symbols are in completely different places, require modifiers, and thus you almost get cramps when typing some keyboard shortcuts. On a “default” English keyboard, they’re easy and the placement makes sense.
It's a little annoying but overall not too bad. Don't need the additional modifiers but I no longer have ZXCV next to each other. I usually have two hands at the keyboard anyway.
This. Using QUERTY immediately feels uncomfortable when i have to use it. Learned NEO2 which has layers accessed with modifier keys. Having a numpad under your hand is one of its' many advantages.