[orangea]

- Doesn't allow installing multiple versions of packages at the same time

- In practice, requires being installed to /usr/local

- Hard to uninstall in practice, leaves files scattered behind

[kikimora]

It allows multiple versions, but only one can be linked. Never needed anything from homebrew in /usr/local, why do you need it? I don’t know if it leaves anything after uninstall, maybe config files in the home directory?