| Taking your B12 supplements is not a guarantee: https://pubmed.ncbi.nlm.nih.gov/35253567/ Checking your B12 levels is not a guarantee either, since the mechanism of deactivation still makes the B12 detectable in a blood test. The inactivation can last for a few days. For frequent users, getting pins and needles in your feet is fairly common, and with prolonged use it can lead to "subacute combined degeneration of the spinal cord". The good news is the effects are mostly reversible if you aggressively supplement with B12 and perhaps the B12 cofactors, and stop using nitrous. If you do a search (https://pubmed.ncbi.nlm.nih.gov/?term=%22Nitrous+Oxide%2Fadv...) neuro effects are most common, but but there are also reports of thrombosis, bladder issues, and sexual disfunction. Some decent papers are https://pmc.ncbi.nlm.nih.gov/articles/PMC10447413/ and https://pmc.ncbi.nlm.nih.gov/articles/PMC10442242/ I'm not a medical doctor, but the metabolic processes are fascinating, akin to background garbage collection or other maintenance processes in software. And like those, they are subject to bugs or other interruptions. |