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by smiley1437 588 days ago
Did you know you can buy an Oxford Nanopore sequencer for about $2000 euro? It sits on your desk and it will sequence DNA or RNA at about 450 bases per second

https://nanoporetech.com/platform/technology

It somehow grabs a free strand of DNA\RNA and pulls it through a specially constructed pore on a membrane. It reads the voltage change as it goes through because each type of base (ATGC) changes the voltage differently, and interprets the sequence and outputs the data in a file.

Doesn't even need PCR amplification because it reads a single strand.

I thought it must be fake because it sounds like something out of science fiction but Nature did an article:

https://www.nature.com/articles/s41587-021-01108-x

Mind blowing

1 comments

What's the accuracy of this compared to commercial sequencing services, and what's the actual TCO? Can 20 people do a group buy for one machine, and use it to get truly private DNA sequencing for $150 ($100 capex + $50 for consumables)?