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I think it's important to call out that it's actually constantly increasing amount to increase the results. As patients lose weight, they need to eat fewer and fewer calories to continue to lose weight, as the BMR decreases. This isn't because of the medication, but rather because it requires fewer calories to maintain their mass, so they burn fewer calories at rest. Increasing the dose further decreases hunger signals, which further decreases their desire to eat as much. It's not "increasing to maintain the same results" its "increasing to increase results". Ex. Patient A currently weighs 330lbs. Has a BMR of 3300 Calories.
- Initial dose, they eat 2,800 calories a day instead of 3,500 calories they used to.
- Loses weight. Now weighs 250lbs.
- BMR is roughly now weighs 250lbs, and has a BMR of roughly 2500 calories, but dose still has them eating around 2,800 calories.
- Dose is increased, patient is now eating around 2,000 calories.
- Patient A reaches 200lbs, BMR is roughly 1,800 calories, but is still eating 2,000 calories.
- Dose is increased, Patient A is now eating 1600 calories. |