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by dmicah 604 days ago
There have previously been associations between caloric intake and Alzheimer Disease or Cognitive Aging, for example:

https://jamanetwork.com/journals/jamaneurology/fullarticle/7... https://www.pnas.org/doi/10.1073/pnas.0808587106

1 comments

I think it's a fair bit of a stretch to broadly say that this study shows an association.

> Conclusion: Higher intake of calories and fats may be associated with higher risk of [Alzheimer Disease] in individuals carrying the apolipoprotein E ϵ4 allele.

> The hazard ratios of [Alzheimer Disease] for the highest quartiles of calorie and fat intake compared with the lowest quartiles in individuals without the apolipoprotein E ϵ4 allele were close to 1 and were not statistically significant.

For the general population, there was no correlation. Identifying specific genetic outliers where there may be a connection is still useful, but far from a general result.