[saalweachter]

The biggest thing we're doing now is accumulating a huge amount of genetic diversity, full of all sorts of novel mutations and interesting admixtures.

It's hard to know what genes or traits will be advantageous over the next centuries. The biggest place where our technological advantage still has large gaps that our biology can compensate is disease, and there it's almost random -- a gene that results in a novel protein which is normally advantageous or disadvantageous might have the opposite effect if it makes you exceptionally vulnerable or resistant to a new disease.