[Someone1234]

> So far, I haven't seen much evidence that GLP-1s have a positive effect on people who aren't overweight.

It is licensed, tested, and sold as a Type-2 Diabetes medication. Are you claiming it is ineffective for that purpose? Or if you're under the impression that no healthy weight T2 Diabetics exist, I have some news for you...

It is also being studied for: opioid addiction, alcoholism, Alzheimer's/Parkinson’s, Cardiovascular Disease, NASH, and PCOS.

"So far, I haven't seen evidence" may be more related to what you have read than what is available for you to read.

[jewayne]

Don't dismiss the most important question -- does semaglutide really have any effects outside its current intended use for diabetes and weight loss?

In other words, would a thin, metabolically healthy person benefit from taking semaglutide?

So far, all of the wonderful benefits from taking the drug seem to be explainable by reduced caloric intake / weight loss / better glucose control in overweight and/or diabetic people.

[Someone1234]

> In other words, would a thin, metabolically healthy person benefit from taking semaglutide?

That's what this thread is about; and multiple other studies looking at different diseases/illnesses/addictions. Time will tell. It is currently approved for T2 Diabetes and Obesity.

[jewayne]

There's also the intriguing possibility that many other diseases and even addictions have a heretofore-unknown metabolic component. The idea of some addictions -- even to things like heroin or gambling -- being partially metabolic does not seem far-fetched to me.