I have a bunch of esp32-c3 and build system of capibaraZero make it easy to integrate it(like other device of esp32 family). The only problem with esp32-c3 is the absence of USB OTG feature.
Not really a requirement, you won't see USB section on the GUI. The capibaraZero is designed to support almost every device that support Arduino Wiring framework, so if a device doesn't support a feature, it will be hidden in GUI
I have a bunch of C3-mini boards and it would be great to finally use them for something more interesting than a temperature sensor.