[tsimionescu]

Sure, a bigger rocket could carry this particular payload while being reusable. But for any rocket there will always be payloads it can't carry while also having enough fuel to land.

[dotnet00]

That constraint can be significantly mitigated by in-space refueling. Then it just becomes a matter of what the rocket can lift into a stable orbit.

Edit: Not that this applies to any currently operational rockets.