[throw4950sh06]

Mainly VAT and related accounting, which is universal. Also consider that EU doesn't think investment into software development is actually investment - not fully tax deductible. There are ways around that but you're going to need an expensive accountant/tax consultant on a daily basis.

[leviliebvin]

Wow, that puts a damper on the whole thing.

[getwiththeprog]

Don't believe they hype. Startups come from all over. You need to demonstrate a sound understanding of your product and your pathway. You need to have other people on board and believing in you. You probably do not need to hire two programmers at market rates and rent GPUs. You need partners. And don't be afraid to cut others in on the deal.

A lot of great stuff is coming from Poland and Czech Republic - hard workers, smart people and low cost of living. You will have to sacrifice something in the early days.

[throw4950sh06]

Indeed, and all of the good startups are incorporated in the US. I work in this area (PL, SK, CZ, HU). Definitely don't incorporate here if you can avoid it, it's so much trouble that can be avoided by simply going elsewhere.