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by franga2000 615 days ago
Ok but now you're not comparing drug vs no drug but drug vs other drug. Yes it can be blind, but it's a cometely different study now
1 comments

Suggestion alone can make you feel high. I remember someone telling me that he got high just by touching sweaty people in a music festival where most people were high, clearly, that's placebo. And that guy was far from drug-naive.

And they sometimes give active substances to the control arm to have an effect. I remember in a covid vaccine trial, they gave the meningitis vaccine to the control group to mimic the side effects of the covid vaccine they tried. Here, they actually gave a microdose of psilocybin (1mg) to the SSRI arm. I don't know why, but maybe it was enough for them to feel something without having the full effect.