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by throwawaymaths
620 days ago
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Forget Rosetta. Even installing that shit was hard, and running it on a sufficiently beefy machine was probably really not a thing in the late aughts. For protein design you mostly just need a quick and dirty estimate of what it looks like, and you have friend proteins that can be used to homology map, you could just use phyre/phyre2, which is an online threading model and be close enough to get work done. Upload the pdb, upload the sequence, bing bam boom. |
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