[scorpioxy]

Whether something is simple or not I'd say depends on the use case. But I found borg to be great. I'd recommend you check it out and go through the quickstart guide in the documentation. It does de-duplication and encryption. It does a lot more but you don't have to use those features if you don't need them. I couple it with borgmatic to implement a backup and disaster recovery procedure that is meant to decrease the risk of data loss. I also use borgbase and they have a good service but using something like B2 with this rclone support would result in a cheaper alternative if you don't need the extra that borgbase provides.

I've been using it for quite a while now both for my personal projects and paid work and have had a good experience with it.