[cess11]

You can invent another syntax with Lisp/Scheme macros if you want. When compiled or interpreted it will be macro-expanded, and then likely transpiled to an AST and then compiled into byte- or machine code.

Take a look at Racket languages for some examples.

Lisp syntax with the parens and so on means editing is inherently structural, which makes it relatively easy to reason about and restructure the code. In Python spaces have double meanings, both as separator between tokens and as a block separator, similar to e.g. {} or () in other languages. That makes structural editing relatively hard.

[codr7]

Read macros, ordinary macro bodies have to follow ordinary syntax rules.