It took only 17 Space Shuttle flights before a crew-member threatened to kill themselves causing them to add additional locks to the hatches. I think a few seconds considering what a malicious actor could do would be worth it.
I don’t know what argument you’re trying to make. The question is: should the ISS be hardened against someone on LSD. My answer is: that is fucking absurd, and generic hardening against malicious actors is tangential at best.