[drivingmenuts]

I am running up against it now. While QT works on the major OSes, it somehow manages to not quite fit with the design of the OS - which drives me crazy. If I wanted it to sort of behave like a Windows app, I'd write Windows apps. Sadly, it's the best option for Python.

[hermitcrab]

I think Qt looks and feels pretty native on Windows. It doesn't look quite as native on Mac, but it's not far off.