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by RobotToaster 655 days ago
If it dissolves in DMSO, penetration should be vastly improved.
2 comments

It is stated to be slightly solvable in DMSO, so that may be already enough. Anyway, i've got the impression - layman from reading some related articles - with DMSO the solubility isn't that important in the sense that DMSO seems to be temporarily increasing physical permeativity of the tissues - kind of creates micropores - so that even some not very soluble stuff can probably get through. I have a small bottle of DMSO at home, wonder if should buy some Doritos on the way home :)
What kind of application are you suggesting with DMSO?

t. chem student

probably mixing dmso with tartrazine and rubbing it on thin skin. dmso is commonly used as an excipient to promote dermal penetration (of the stratum corneum) by drugs in topical preparations

see https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460663/