[shiroiushi]

>Could it be that you get less wrist pain because Dvorak switches things up rather than it being better overall?

No. It's because you don't have to do hand contortions with Dvorak the way you do with qwerty. If you want a demonstration, try typing "minimal" on both, and watch your hands carefully. On qwerty, it's almost all on one hand, and alternating between top and bottom rows. On Dvorak, it's alternating between hands (which is always better). You can see similar things with any English text of decent length: Dvorak makes you alternate between hands far better, and far more of your typing is on the home row (esp. since the vowels are all on the home row).

[Aerroon]

But is that really good? I can increase my sensivity very high on my mouse, where I barely have to move the mouse. However, this does cause me more pain than low sensitivity instead. High sensitivity makes me move the mouse almost entirely with the wrist, where low sensitivity uses the wrist and forearm.

I don't know if the same applies to typing, but I can see a mechanism where it is.