[Sysreq2]

This reminds me of a conversation I was having recently about genetically engineering humans. I think people are greatly underestimating the complexity of the human body and it’s nature mechanisms of adaptation. Everyone is a little different - but that’s okay because all the little feedback loops and receptor sites account for changes. Like a drug addict needing more and more to get their fix. There isn’t just one variable we can adjust to really solve most problems. You have to look at the entire web of interconnected systems and modulate how each of them work together. We sort of take it all for granted since life is so abundant, but it’s truly nothing short of miraculous.

[FeepingCreature]

Though arguably this should also make it easier to make changes, because the body already has to cope with so much natural variation.

[taneq]

But then you fix the problem at the wrong control-loop level and after a while it goes right back to how it was.

[ProllyInfamous]

>truly nothing short of miraculous.

Here by the grace of god(s)...

The brain is but just one part of an incredibly complex machination.

[lanstin]

Also one substance can be used in multiple feedback loops in different tissues. Tweaking one loop without touching others will take some finesse.