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by gmaster1440 654 days ago
AlphaFold is really impressive and made scientific advancements and discoveries in the field of protein folding, and is now even expanding into more molecules and biology, but it was explicitly trained to do just that. You're not going to see AlphaFold write compelling science fiction.

We can build models that are specifically trained and fine tuned on scientific fields to make advancements in them, but that's different from what I'm talking about, which is building a model that forms its own hypothesis, designs its own experiments, and contributes to the wide and deep wealth of knowledge that, crucially, goes well beyond the scope of its training data.

1 comments

Ah, sorry, I was editing while you responded.

> You're not going to see AlphaFold write compelling science fiction.

Yes? But not many biology PhDs do that either.

> I'm talking about, which is building a model that forms its own hypothesis, designs its own experiments, and contributes to the wide and deep wealth of knowledge that, crucially, goes well beyond the scope of its training data.

A few weeks ago we saw LLMs do the first half of that. I think AlphaFold demonstrates the last.

Don't get me wrong, I trust the person who told me these are not good papers, but it does do those things: https://sakana.ai/ai-scientist/

I'm happy to leave the conversation here. I don't necessarily disagree with what you're saying, but we appear to be making different points, or at least at different levels of description, and it's not really productive anymore.
Certainly, my confusion would be compatible with that.

Have a good weekend :)