The Rust wgpu project has an alternative C API which is identical (or at least closely matches, I haven't looked in detail at it yet) the official webgpu.h header. For instance all examples in here are written in C:
First of all, it doesn't support RenderGeometry or RenderGeometryRaw, which are necessary for high-performance 2D rendering (absent the new GPU API). I doubt it will support any of the GPU API at this rate, as the geometry rendering is a much simpler API. Maybe both will land all at once, though. To wit, the relevant issue hasn't seen much activity: https://github.com/Rust-SDL2/rust-sdl2/issues/1180
Secondly, the abstractions chosen by rust-sdl2 are quite different from those of SDL2 itself. There seems to have been an aggressive attempt by the Rust library authors to make something more Rust-friendly, which maybe has made it more approachable for people who don't know SDL2 already, but it has IMO made it less approachable for people who do know SDL2. The crate gets plenty of downloads, so maybe it's just me.