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Calorie restriction is actually one of the fiew proven longevity tricks.

Nothing proven about it.

In mice anyway.

Not exactly. The calorie restricted mice do live longer unless they get an infection or some other unexpected source of stress, then they die at much grater rates. It is as if they have no reserves.

In humans calorie restriction is absolutely and utterly unproven.

Humans and mice are very different. They are tiny short lived animals, and we are large long lived animals. That is why a lot of the cancer cures you hear about in mice don't work in humans. Because often we already are born with them. There are known tumor suppressing genes, humans have more copies of them than mice, elephants have even more.

This is why it is not reasonable to assume that simple hacks like calorie restriction, which work in mice... sort of, will also work in humans.

A health diet and exercise on the other hand, have been proven to work in humans.