Ditto from Phase 1 to Phase 3. Side effects always an issue. One could say only half in jest that humans are not particularly good models for humans. Exceedingly expensive and all kind of environmental and compliance confounders.
At least when using rodent you can control the environmental factors in a randomized controller “clinic” trials. Compliance not so hard to ensure.
At least when using rodent you can control the environmental factors in a randomized controller “clinic” trials. Compliance not so hard to ensure.