[azinman2]

Does tolerant mean ok to do? Or it just won’t fry your chip but you should actually run at 3.3?

[murderfs]

5V tolerant means that it'll accept 5V input (and correctly interpret it as high), but output will still be 3.3V.

[tredre3]

It usually means it's clamped so it might result in a small amount of wasted energy/heat but no damage.

So yes it means it's okay but if you can you should go for 3.3.