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by sddsdd 681 days ago
It does in fact prevent infection you have misunderstood.

It very clearly prevents infection incredibly well, proof of that in the real world is exactly why there is excitement over this drug.

It also sounds as though you misunderstood the mechanism, it interferes in both an early and a late step in the viral process, there no theoretical reason to describe it as "not interfering with infection".

1 comments

From what I read, it interferes with capsid formation. Since HIV is a retrovirus, by the time capsid formation is happening it has already integrated itself with the host cell’s DNA.

That implies that as long as the drug is present, the virus won’t be able to replicate, however as soon as the drug is no longer present the virus will start replicating. Because the cell has been infected.