This is just what life is... We can spend all day talking about fairy tales of living forever but this is reality lol. What position is there to rethink ?
Wrote the commentor on a sheet of glass and metal, sharing their thoughts at the speed of light over a planet-spanning communications network with thousands of nodes in low-Earth orbit, while others on that network acts as patrons to sponsor such research as "can we grow mouse fibroblasts in gatorade and other soft drinks as part of an ongoing project to build a meat robot?" (the answer, is this is surprisingly more viable than they expected).
It's very easy to be overconfident where the boundary is between fairy tales and engineering, the boundary between fairy tales and science is even harder, and even domain experts can get that wrong in both directions.
That evolution be allowed to operate unencumbered by mitigation on human populations is literally a eugenic position. It's not necessary to identify specific genes or traits that evolution would act on for this to hold.