Hacker News new | ask | show | jobs
by THBC 693 days ago
It’s only the irreversible MAOIs that get a bad rap for being somewhat incompatible with certain foods and other medicines.

These MAOIs are reversible, i.e. they will release from their substrate (the MAO enzymes) after some time. Irreversibles require the body to synthesize more of the enzyme to replace the enzyme molecules that got forever inactivated.

That said, some of the Harmala family alkaloids are also heavily comutagenic and some are neurotoxic.