[RamblingCTO]

The big differentiator for me is possible harm and addiction. Psychedelics don't typically bring both (I am under the impression, that we actually don't really know how schizophrenia and psychosis relates or is triggered by psychedelics, that was my impression of recent research). Using crack, heroin etc. and "designer drugs" etc. is a whole other thing. Safety of consumption is just on another level for both classes. Even with "designer" psychedelics that are just added molecules. Tbh I don't know about any totally and weird synthetic psychedelics, I'm assuming shrooms, LSD/AL-LAD (which are both of course synthetic as well), mescaline, ibogaine, and DMT essentially. I hope everyone reading get's the distinction I'm trying to make.

[LoganDark]

Yes, I understand. Serotonergic psychedelics are typically not big sources of addiction, and they typically only cause great harm if taken incorrectly or by someone with a genetic predisposition towards schizophrenia or psychosis; though even then, the harm is only really psychological (but it can be permanent).

Please do note, however, that there are psychedelics which are not serotonergic psychedelics, such as psychedelic amphetamines. These are not typically nearly as safe, just as amphetamines in general typically are not particularly safe when used incorrectly.