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by kapitanjakc 697 days ago
Dumb question here :-

My father has diabetes since he was 30, my grand father had it too in his 30s.

I am beginning my 30s, will I get it too ?

Is it guaranteed that I'll get it ?

Can I avoid getting it ?

Both my father and grandfather had heart attacks...

4 comments

It depends on genetics and luck.

The luck part is that it seems that infections trigger the autoimmune reaction that kills the pancreas. The genetics bit is that you may or may not have got the gene from your father.

Most people die of heart attacks in the end. Factors like smoking, lifestyle and fighting in wars are probably more important than well managed type 1 nowadays. The big difference now is that the insulin is human insulin, made by genetically engineered microbes. In the past it was harvested from animals and it didn't work as well. Also constant blood monitoring means that highs and lows can be detected and fixed before damage is done. So - things have moved on, there isn't as much to be frightened of, I'm sorry your dad died young, but you will probably be ok.

Not a dumb question. You are damn near guaranteed to get type 1 diabetes if you test positive for two or more T1D autoantibodies and/or your A1C is 5.7 or higher. Both can happen before you show any symptoms of T1D.

Get blood test for all five Type 1 Diabetes Autoantibodies: (this can be done for free) GADA IA-2A IAA ZnT8A ICA

Get blood test for pancreatic C-peptide.

Get blood test for A1C.

Check out tzield if you test positive.

I can share sources if you’re interested. I’m. T1D.

I can't answer this question for you, but some life-style factors which I think will help you avoid getting it are provided below:

- 5-10g of vitamin D daily (assuming you're talking about type 1 diabetes) - type 1 diabetes is an auto-immune disease, and vitamin D plays a huge role in regulating our immune systems. In fact, type 1 diabetes is more prevalent for those who move from warmer countries to colder ones where there's less sunlight that those who do the opposite.

- Exercise: probably the single best thing you can do for your brain and body, and does a wonder in regulating the immune system and helps out many with not just diabetes, but with a ton of other disorders and the higher intensity the exercise, the better. Exercise which increases your VO(2) max here is the best - both strength training and interval training are highly effective.

- Intermittent fasting (and staying lean): assuming that you're attempting to avoid type 2 diabetes, there's great evidence that IF (intermittent fasting) can put it in remission: https://www.endocrine.org/news-and-advocacy/news-room/2022/i...

- Minimally processed and ketogenic diet: avoid foods which have sugar or high-fructose corn-syrup on the ingredients list. In fact, in my case, I try to avoid any foods with more than 5 ingredients and try to stick to mostly a plant based and keto diet (this definitely helps with type 2 diabetes). Also avoid high-glycemic index foods (high-glycemic here means ability to 'spike' sugar and you can find the glycemic index of most foods through a simple good search. More info on this index: https://en.wikipedia.org/wiki/Glycemic_index ).

- Take a teaspoon with turmeric + black-pepper daily: 'Clinical trials and preclinical research have recently produced compelling data to demonstrate the crucial functions of curcumin against T2DM via several routes. Accordingly, this review systematically summarizes the antidiabetic activity of curcumin, along with various mechanisms. Results showed that effectiveness of curcumin on T2DM is due to it being anti-inflammatory, anti-oxidant, anti-hyperglycemic, anti-apoptotic, anti-hyperlipidemia and other activities. In light of these results, curcumin may be a promising prevention/treatment choice for T2DM.' - Source: https://www.preprints.org/manuscript/202404.1926/v1

> Can I avoid getting it ?

Yeah, by losing weight. Unless the reason they got it is because of some autoimmune timebomb that's genetically programmed to go off in the 30s and destroy the pancreas.

FFor more context:

Type 1 diabetes (T1D) is an autoimmune disease. Your own immune cells attack your insulin-producing beta cells in your pancreas, leading you to lose the ability to produce insulin to absorb glucose from the blood. You will lose weight, be frequently thirsty, and have to pee frequently. T1D seems to have a genetic factor which you can be tested for.

Type 2 diabetes (T2D) is a lifestyle disease where you become less sensitive to the insulin that your body produces. It can be prevented by maintaining healthy diet, exercise, and weight, and it can usually be detected early as prediabetes. There may be a genetic factor predisposing you to T2D, but I don't know if there are tests for it.

You need to know which disease your family had to know which answer it is. They are two totally different diseases that just happen to both be related to insulin.