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by w10-1 718 days ago
> What do you think the mechanism behind this is

Estrogen in the brain is neuro-protective and neuro-trophic. The primary source of estrogen in the brain for men is testosterone converted via aromatase.

However, that's speculative. I found no significant studies on point, notwithstanding physician interest. Because some men seek out testosterone, some doctors might be quick to offer it off-label for other conditions.