[epgui]

This is an incredible perspective coming from a 16 y/o.

For what it’s worth, it took me spending 12+ years studying biochem and adjacent topics at university, to reach a very similar perspective.

The one criticism I’d make here (and tbh it’s unfair to expect more from the author) is that there has been a lot of work done towards this already. There are many systems biology textbooks, a much greater number of systems papers, and even entire journals on the subject. So I would reframe the observations slightly: there is a lot of prior work, and we need to double down on it and cross-pollinate it more.

[hdarshane]

Thank you so much for the kind words! I'm definitely a little ignorant with respect to systems biology efforts. I have an okay-ish idea of the work of someone like Uri Alon, it's definitely not enough. What resource would you recommend for me to jump into? Uri Alon's course? I believe I lack many pre-requisites to take it.

[epgui]

To be honest I'm not really sure what advice to give you. You're probably in a spot where your knowledge/perspective is advanced enough to make you impatient around the fundamentals, and at the same time I'm not sure that you have the background required to take full advantage of more advanced materials. You don't seem to be where most 16 year olds are, is what I'm trying to say.

This is especially tricky in the field of bio / biochem, which feels like it requires memorizing a million facts before one gets to do any real thinking and reasoning. This unfortunately tends to filter out a lot of more mathematically-minded people who are stimulated by puzzles, which I think is a shame.

For what it's worth, I really enjoyed this textbook. I'm not sure you will find in it what you're hoping to find, but I hope it sparks even more curiosity; it's fairly advanced, probably more targeted at late-BSc or MSc/PhD students: https://www.amazon.com/First-Course-Systems-Biology/dp/08153...

[hdarshane]

>This is especially tricky in the field of bio / biochem, which feels like it requires memorizing a million facts before one gets to do any real thinking and reasoning. This unfortunately tends to filter out a lot of more mathematically-minded people who are stimulated by puzzles, which I think is a shame.

yes, this is exactly the part that makes it really really hard...

thanks a lot for the recommendation!