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I think things like the opioid crisis where doctors were getting outright bribes from pharmaceutical companies who knew they were killing people has done a massive amount of harm to the trust people had in medical science. It's been a problem for a long time, even going back to the tobacco industry hiring researchers to lie about the dangers of smoking. Those researchers didn't lose their jobs and become unhireable in their fields. They just went on to work for the oil companies to lie about how climate change isn't real and are now working for companies currently trying to convince the FDA about the safety of food additives.

Between corporations being able to buy whatever research they think will get them a favorable headline, peer reviewed journals accepting any paper if you pay them to publish it (this one being a personal favorite https://www.sciencealert.com/a-neuroscientist-just-tricked-4...), the reproducibility crisis more generally, the total lack of any meaningful consequences when companies are caught outright knowingly poisoning people or selling dangerous drugs, it's really getting harder to explain to people at the fringes like antivaxxers why they should have more faith in the data we have and on the systems put in place to protect them.

If the people aren't held accountable for causing harm and scientists don't do a much better job self-policing I think the situation is only going to get much worse. Even if things do change it will likely take generations to undo the damage already done.