[digital_sawzall]

Fuzzing is a massive field now. I don't know what you are doing specifically but this is a collection of good related papers: https://github.com/wcventure/FuzzingPaper.

I would find what is most like your problem domain and dig in :).

[zEddSH]

I've been doing the simplest possible things to URL parameters and POST bodies but even that's been effective! Thanks for the link!